BEGIN:VCALENDAR VERSION:2.0 PRODID:-/-/EN BEGIN:VEVENT SUMMARY:General Internal Medicine – Core Topics (Autumn 2025) UID:1174 DESCRIPTION:2.00 pm\nA brief Annual General Meeting of the Section of Medicine will take place immediately prior to the symposium to formally elect new Office bearers and members of Council.\n\n2.05 pm  \nPharmacotherapy for obesity: the past, the present and the future\nProfessor Akheel Syed, Consultant Physician in Diabetes & Endocrinology, NCA Foundation Trust (Salford Royal Hospital) where he leads the specialised severe and complex obesity service\n\nTalk synopsis:\n\nObesity is a major global determinant of health of our time. Whilst lifestyle, dietary and behavioural modifications are the cornerstones of weight management, pharmacological interventions are increasingly necessary for a significant number of people living with chronic obesity. Historically, weight loss medications have been limited by poor efficacy, significant adverse effects and poor tolerability, and poor sustainability. Thus, bariatric surgery has been the most effective treatment for  chronic/severe obesity. The advent of incretin-based anti-obesity medications has revolutionised the treatment of obesity and associated diseases. Emerging medical therapies hold the promise of ever greater clinical effectiveness, potentially obviating the need for bariatric surgery.\n\n2.45 pm\nAsthma diagnosis and misdiagnosis: solution lies within the 4th dimension \nDr Ran Wang, NIHR Clinical Lecturer, University of Manchester and ST7 Respiratory Medicine, Manchester University NHS FT\n\nTalk synopsis:\n\nAsthma is common affecting 10% of the UK population. Of 160,000 new diagnosis per year, up to one in three are misdiagnosed. Asthma is defined by symptoms and airflow obstruction that fluctuates over time. Despite the hallmark of asthma is its temporal variability, current clinical practice still approaches the condition as if it was a static disease.\n\nIn this lecture, I will summarise the current diagnostic challenges in asthma and highlight how time is the missing dimension in asthma care. I will demonstrate how diurnal, day-to-day and longer-term fluctuations can influence our clinical decision-making and present evidence that using domiciliary monitoring and demonstrate how longitudinal test measurements capturing the variability in asthma pathophysiology can better improve asthma care.\n\nThese findings underscore the need to move beyond static, one-size-fits-all approaches towards diagnostic strategies that recognise time as a critical dimension in asthma. In response to the mounting evidence, the Global Initiative for Asthma 2025 guidance has incorporated the influence of test timing into their diagnostic recommendations. Advances in digital health pave the way for harnessing temporal variability in diagnosis and treatment, opening new horizons for truly personalised asthma care.\n\n3.25 pm\nCoffee break\n\n3.45 pm\nRash and other skin eruptions whilst taking medication(s). Is it an allergy?\nDr Marina Tsoumani, Consultant Allergist, Manchester University NHS FT (Wythenshawe)\n\nTalk synopsis:\n\nClinical presentations of drug related rash/urticariaPitfalls and challenges in drug (cutaneous) allergyEarly recognition of severe drug cutaneous reactionsApproach to the patient with rash whilst on medicationsDrug allergy as a working diagnosis – then what?Main management strategies4.25 pm\nMeeting close\n\n \n\nAttendees will receive a CPD certificate of attendance\n\n \n\n DTSTART:20251007T130000Z DTEND:20251007T153000Z LOCATION:MANDEC - 3rd Floor, University Dental Hospital, Higher Cambridge Street, Manchester M15 6FH END:VEVENT END:VCALENDAR